Silencing ataxin-3 mitigates degeneration in a rat model of MachadoJoseph disease: no role for wild-type ataxin-3?

By Alves Sandro   Nascimento-Ferreira Isabel   Dufour Nolle   Hassig Raymonde   Auregan Gwennalle   Nbrega Clvio   Brouillet Emmanuel   Hantraye Philippe   Pedroso de Lima Maria C.   Dglon Nicole   de Almeida Lus Pereira  

Human Molecular Genetics, Vol. 19, Iss. 12, 2010-06 ,pp. : 2380-2394

Oxford University Press

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Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3)

By Hübener Jeannette   Weber Jonasz Jeremiasz   Richter Claudia   Honold Lisa   Weiss Andreas   Murad Fabronia   Breuer Peter   Wüllner Ullrich   Bellstedt Peter   Paquet-Durand Francois   Takano Jiro   Saido Takaomi C.   Riess Olaf   Nguyen Huu Phuc  

Human Molecular Genetics, Vol. 22, Iss. 3, 2013-02 ,pp. : 508-518

Oxford University Press

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Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3

By Haacke Annette   Broadley Sarah A.   Boteva Raina   Tzvetkov Nikolay   Hartl F. Ulrich   Breuer Peter  

Human Molecular Genetics, Vol. 15, Iss. 4, 2006-02 ,pp. : 555-568

Oxford University Press

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The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity

By Burnett Barrington   Li Fusheng  

Human Molecular Genetics, Vol. 12, Iss. 23, 2003-12 ,pp. : 3195-3205

Oxford University Press

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Proteotoxic stress increases nuclear localization of ataxin-3

By Reina Christopher P.   Zhong Xiaoyan   Pittman Randall N.  

Human Molecular Genetics, Vol. 19, Iss. 2, 2010-01 ,pp. : 235-249

Oxford University Press

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