Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models

By Tauffenberger Arnaud   Chitramuthu Babykumari P.   Bateman Andrew   Bennett Hugh PJ.   Parker J. Alex  

Human Molecular Genetics, Vol. 22, Iss. 4, 2013-02 ,pp. : 782-794

Oxford University Press

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Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis

By Farg Manal A.   Soo Kai Y.   Warraich Sadaf T.   Sundaramoorthy Vinod   Blair Ian P.   Atkin Julie D.  

Human Molecular Genetics, Vol. 22, Iss. 4, 2013-02 ,pp. : 717-728

Oxford University Press

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Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes

By Diaper Danielle C.   Adachi Yoshitsugu   Sutcliffe Ben   Humphrey Dickon M.   Elliott Christopher J.H.   Stepto Alan   Ludlow Zoe N.   Vanden Broeck Lies   Callaerts Patrick   Dermaut Bart   Al-Chalabi Ammar   Shaw Christopher E.   Robinson Iain M.   Hirth Frank  

Human Molecular Genetics, Vol. 22, Iss. 8, 2013-04 ,pp. : 1539-1557

Oxford University Press

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RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations

By Daigle J. Gavin   Lanson Nicholas A.   Smith Rebecca B.   Casci Ian   Maltare Astha   Monaghan John   Nichols Charles D.   Kryndushkin Dmitri   Shewmaker Frank   Pandey Udai Bhan  

Human Molecular Genetics, Vol. 22, Iss. 6, 2013-03 ,pp. : 1193-1205

Oxford University Press

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Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS

By Estes Patricia S.   Boehringer Ashley   Zwick Rebecca   Tang Jonathan E.   Grigsby Brianna   Zarnescu Daniela C.  

Human Molecular Genetics, Vol. 20, Iss. 12, 2011-06 ,pp. : 2308-2321

Oxford University Press

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