Endogenous Angiotensins, Angiotensin Ii-Competitive Binding Inhibitors and Converting Enzyme Inhibitor in Elasmobranch Fish

Author： Hazon N.  

Publisher： Brill

ISSN： 1568-542X

Source： Netherlands Journal of Zoology, Vol.45, Iss.1-2, 1994-01, pp. : 117-120

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Abstract

This study demonstrates the potent vasopressor activity of homologous dogfish angiotensin (A) I and II. The AII competitive binding inhibitors [Sar1-Val5-Ala8]-AII and [Sar1-IIe8]-AII did not inhibit the pressor action of dogfish AII but the converting enzyme inhibitor captopril effectively blocked conversion of AI to AII.

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