In Vitro Antimicrobial and Nematocidal Activity of Acetogenins Identified from Exocrine Secretions of Stephanitis and Corythucha Lace Bug Nymphs (Heteroptera: Tingidae)

Author： NEAL JOHN W. OLIVER JAMES E. FETTERER RAYMOND H.

Publisher： Entomological Society of America

ISSN： 1938-2901

Source： Annals of the Entomological Society of America, Vol.88, Iss.4, 1995-07, pp. : 496-501

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Abstract

Lace bug nymphs of the genera Corythucha and Stephanitis have secretory setae with microdroplets distributed over their body (including antennae), from which novel acetogenins have been identified. Selected lace bug acetogenins, synthetic analogs, and synthetic compounds of plant origin were evaluated for biological activity against common microorganisms and the parasitic nematode Ascaris suum (L.). Ten of the 12 lace bug-derived and related synthetic compounds tested were active in a disk diffusion test that challenged 9 bacteria and 9 fungal pathogens; of the 10 compounds causing zone inhibition, 6 were active against 3 or more species of bacteria. Zone inhibition occurred against only gram-positive bacteria which included Bacillus subtilis (Ehrenvberg) Cohn, Clavibacter michiganense subspecies michiganese (Smith) Davis, Gillaspie, Vidaver & Harris, Rhodococcus facians (Tilford) Goodfellow, Actinomyces bovis Harz, A. naeslundi Thompson & Lovestedt, and Corynebacterium diphtheriae (Kruse) Lehmann & Neumann. Activity against gram-negative bacteria was minimal. In a 2nd test with only gram-positive organisms, the bacteria C. michiganense, R. facians, and C. diphtheriae produced the largest zones. There was no inhibition of growth by 4 species of plant fungi and 5 insect fungal pathogens. Two compounds stunted growth of A. suum larvae with growth inhibition similar to that caused by anthelmintic standards.