A role for epithelial γδ T cells in tissue repair

Author: Havran Wendy  

Publisher: Humana Press, Inc

ISSN: 0257-277X

Source: Immunologic Research, Vol.21, Iss.2-3, 2000-06, pp. : 63-69

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Abstract

My colleagues and I have a long-term interest in interactions between intraepithelial γδ T cells and neighboring epithelial cells. We have focused our studies on interactions in the thymus, skin, and intestine, and are investigating the development, specificity, and function of these γδ T cells. Our results have defined unique properties of these cells and support a specialized role for epithelial γδ T cells in immune surveillance, wound repair, inflammation, and protection from malignancy.