Continuous production of butanol by clostridium acetobutylicum immobilized in a fibrous bed bioreactor

Author： Huang Wei-Cho   Ramey David   Yang Shang-Tian  

Publisher： Humana Press, Inc

ISSN： 0273-2289

Source： Applied Biochemistry and Biotechnology, Vol.115, Iss.1-3, 2004-03, pp. : 887-898

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

We explored the influence of dilution rate and pH in continuous cultures of clostridium acetobutylicum. A 200-mL fibrous bed bioreactor was used to produce high cell density and butyrate concentrations at pH 5.4 and 35°C. By feeding glucose and butyrate as a cosubstrate, the fermentation was maintained in the solventogenesis phase, and the optimal butanol productivity of 4.6g/(L h) and a yield of 0.42 g/g were obtained at a dilution rate of 0.9h−1 and pH 4.3. Compared to the conventional acetone-butanol-ethanol fermentation, the new fermentation process greatly improved butanol yield, making butanol production from corn an attractive alternative to ethanol fermentation.

Related content

Butanol production using Clostridium beijerinckii BA101 hyper-butanol producing mutant strain and recovery by pervaporation

By Qureshi N.   Blaschek H.  

Applied Biochemistry and Biotechnology, Vol. 84, Iss. 1-9, 2000-03 ,pp. : 225-235 (11)

Humana Press, Inc

Access to resources Recommend Favorite

EFFECT OF FERMENTATION PARAMETERS ON BIO-ALCOHOLS PRODUCTION FROM GLYCEROL USING IMMOBILIZED Clostridium pasteurianum: AN OPTIMIZATION STUDY

By Khanna Swati   Goyal Arun   Moholkar Vijayanand S.  

Preparative Biochemistry & Biotechnology, Vol. 43, Iss. 8, 2013-11 ,pp. : 828-847 (20)

Taylor & Francis Ltd

Access to resources Recommend Favorite

A simple structured model for continuous production of a hybrid antibiotic by Streptomyces lividans pellets in a fluidized-bed bioreactor

By Sarrà Montserrat   Casas Carlos   Poch Manel   Gòdia Francesc  

Applied Biochemistry and Biotechnology, Vol. 80, Iss. 1, 1999-04 ,pp. : 39-50 (12)

Humana Press, Inc

Access to resources Recommend Favorite

Butanol Production by Clostridium beijerinckii BA101 in an Immobilized Cell Biofilm Reactor

By Lienhardt J.   Schripsema J.   Qureshi N.   Blaschek H.P.  

Applied Biochemistry and Biotechnology, Vol. 99, Iss. 1-3, 2002-03 ,pp. : 591-598 (8)

Humana Press, Inc

Access to resources Recommend Favorite

Decolorization of the anthraquinone dye Cibacron Blue 3G-A with immobilized Coprinus cinereus in fluidized bed bioreactor

By Moutaouakkil A.   Blaghen M.  

Applied Biochemistry and Microbiology, Vol. 47, Iss. 1, 2011-01 ,pp. : 59-65 (7)

MAIK Nauka/Interperiodica

Access to resources Recommend Favorite