A Study on the Influence of Calcified Intervertebral Disk and Aorta in Determining Bone Mineral Density

Author: Cherney D.D.   Laymon M.S.   McNitt A.   Yuly S.  

Publisher: Humana Press, Inc

ISSN: 1094-6950

Source: Journal of Clinical Densitometry, Vol.5, Iss.2, 2002-06, pp. : 193-198

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Abstract

This study utilized dual-energy X-ray absorptiometry (DXA) to determine the association that age-related calcinosis of the aorta and intervertebral disks have in determining bone mineral density (BMD). Eight cadavers were chosen at random and were scanned with DXA before and after the removal of the aorta and intervertebral disks. Our results showed that the removal of sclerotic aortas decreased the vertebral BMD an average of 4.64% and the removal of two lumbar intervertebral disks further decreased BMD an average of 11.93%. These results were deemed significant at the 0.01 level using a Friedman two-way analysis of variance by ranks. It can be concluded that the presence of aortic arteriosclerotic lesions and intervertebral disk chondrocalcinosis add a significant contribution to BMD.