HIV/AIDS-Related Cardiovascular Disease

Author: Chaves Alysia A.   Mihm Michael J.   Basuray Anupam   Baliga Reshma   Ayers Leona W.   Bauer John A.  

Publisher: Humana Press, Inc

ISSN: 1530-7905

Source: Cardiovascular Toxicology, Vol.4, Iss.3, 2004-08, pp. : 229-242

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Abstract

Recent advances in antiretroviral therapies have enhanced survival of HIV/AIDS patients, but cardiovascular complications have emerged as important issues in this growing patient population. Although the antiviral drug therapies apparently yield cardiac and/or vascular toxicities themselves, several other factors associated with HIV pathogenesis have also been implicated. This brief review provides an overview of the significance and complexities of HIV/ AIDS-related cardiovascular complications and addresses some important mechanistic aspects that may contribute to this important clinical problem.