Chronic Invasive Fungal Rhinosinusitis: Two New Cases and Review of the Literature

Author： Dufour Xavier Kauffmann-Lacroix Catherine Roblot France Goujon Jean Michel Breux Jean Philippe Ferrié Jean Claude Klossek Jean Michel

Publisher： OceanSide Publications, Inc

ISSN： 1539-6290

Source： American Journal of Rhinology, Vol.18, Iss.4, 2004-07, pp. : 221-226

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Abstract

Background: Chronic invasive fungal rhinosinusitis is rare in the immunocompetent patient. Few cases have been published except for in a specific geographic area (Sudan, India).Methods and Results: We reported two new cases of chronic invasive fungal rhinosinusitis due to Aspergillus, which was successfully treated, to analyze the different clinical, radiological, and mycological criteria.Conclusion: Through these two new clinical cases and the analysis of the literature, we suggested, in the absence of general agreement on the surgical and medical management, the current strategies available for this rare pathology. New antifungal drugs seem to be an efficient alternative to classic antifungal agents, especially those that require an extended course of oral therapy for the chronic invasive form.