Author： Rajanarendar E. Ramesh P. Srinivas M. Ramu K. Mohan G.
Publisher： Taylor & Francis Ltd
ISSN： 0039-7911
Source： Synthetic Communications, Vol.36, Iss.5, 2006-03, pp. : 665-671
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Abstract
The synthesis of isoxazole-substituted Hantzsch 1,4-dihydropyridines has been achieved by modified Hantzsch procedure for the first time by utilizing ketoamides in place of keto esters on a neutral alumina support in excellent yields. These 1,4-dihydropyridines are aromatized to the corresponding pyridines in high yields by using bismuth subnitrate (BiONO 3 ) adsorbed on acidic alumina at ambient temperature.
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