Author： Rong Liangce Li Xiaoyue Wang Haiying Shi Daqing Tu Shujiang Zhuang Qiya
Publisher： Taylor & Francis Ltd
ISSN： 0039-7911
Source： Synthetic Communications, Vol.37, Iss.2, 2007-01, pp. : 183-189
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Abstract
A simple, efficient, and general method has been developed for the synthesis of coumarin derivatives through a one-pot reaction of aromatic aldehydes, 2,2-dimethyl-1,3-dioxane-4,6-dione and 5,5-dimethyl-1,3-cyclohexanedione, in the presence of TEBA under solvent-free conditions using grinding methods. The mild reaction conditions, simple protocol, high yields, and cleaner reaction make this protocol practical and economically attractive.
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