Triflouroacetic Acid as an Efficient Catalyst for the Synthesis of Quinoline

Author： Shaabani Ahmad   Soleimani Ebrahim   Badri Zahra  

Publisher： Taylor & Francis Ltd

ISSN： 0039-7911

Source： Synthetic Communications, Vol.37, Iss.4, 2007-01, pp. : 629-635

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Abstract

Triflouroacetic acid efficiently catalyzed the Friedländer synthesis of quinolines through a condensation reaction of an 2-aminoaryl ketone with an activated α-CH acid such as cyclic or acyclic β-dicarbonyl or cyclic ketone compounds under solvent-free conditions with high yields within several minutes.

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