Efficient One-Pot Synthesis of Polyhydroquinoline Derivatives Using Silica Sulfuric Acid as a Heterogeneous and Reusable Catalyst Under Conventional Heating and Energy-Saving Microwave Irradiation

Author： Mobinikhaledi Akbar   Foroughifar Naser   Fard Mohammad Ali Bodaghi   Moghanian Hassan   Ebrahimi Sattar   Kalhor Mehdi  

Publisher： Taylor & Francis Ltd

ISSN： 0039-7911

Source： Synthetic Communications, Vol.39, Iss.7, 2009-01, pp. : 1166-1174

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Abstract

An efficient Hantzsch four-component condensation reaction for the synthesis of polyhydroquinoline derivatives was reported under two conditions: solvent-free conventional heating and energy-saving microwave irradiation. The process is simple and environmentally benign, and the use of a heterogeneous and reusable catalyst, high yields, and short reaction times are the key features of this protocol.

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