Synthesis of Benzimidazoles and Benzoxazoles Using Palladium Bis(2,2,6,6-tetramethyl-3,5-heptanedionate) as a Novel Catalyst

Author: Bhor Malhari   Bhanage Bhalchandra  

Publisher: Taylor & Francis Ltd

ISSN: 0039-7911

Source: Synthetic Communications, Vol.40, Iss.12, 2010-01, pp. : 1743-1749

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Abstract

Structurally well-defined palladium bis(2,2,6,6-tetramethyl-3,5-heptanedionate) complex is reported to be an efficient catalyst for the synthesis of benzimidazole and benzoxazole derivatives in good yields. A novel approach for one-pot synthesis of benzimidazoles via direct reductive amination and N-arylation followed by hydrogenation-cyclization methodology is also described.

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