Chemoselective Synthesis of 1,1-Diacetates from Aldehydes Using Anhydrous Cobalt(II) Bromide Under Solvent-Free Conditions

Author: Meshram Gangadhar   Patil Vishvanath  

Publisher: Taylor & Francis Ltd

ISSN: 0039-7911

Source: Synthetic Communications, Vol.40, Iss.3, 2010-01, pp. : 442-449

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Abstract

A mild and efficient method has been developed for the chemoselective preparation of 1,1-diacetates (acylals) from aldehydes catalyzed in the presence of a catalytic amount (0.1 mmol) of anhydrous cobalt(II) bromide under solvent-free conditions. The remarkable selectivity under mild and neutral conditions, excellent yields, short reaction time, and easily available and inexpensive catalyst are important features of this method.

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