

Author: Davis Matthew Groshens Thomas
Publisher: Taylor & Francis Ltd
ISSN: 0039-7911
Source: Synthetic Communications, Vol.41, Iss.2, 2011-01, pp. : 255-261
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Abstract
Friedel-Crafts-type acylation of phenyl ether with 2,5-dichlorobenzoic acid could be accomplished in a single step using trifluoroacetic anhydride and phosphoric acid. The method gave a greater yield (78%) than the conventional two-step process (71%) of acid chloride generation followed by aluminum trichloride-mediated acylation.
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