Homo- and hetero-dinuclear derivatives of aluminium containing Schiff-base ligands: synthesis, characterization and antibacterial activity of mononuclear derivative of aluminium

Author： Vajpayee V. Singh Y. P.

Publisher： Taylor & Francis Ltd

ISSN： 0095-8972

Source： Journal of Coordination Chemistry, Vol.61, Iss.10, 2008-01, pp. : 1622-1634

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Abstract

Reactions of Al(OPri)3 with LH2 = [R'C(NYOH)CHC(R)OH] R=R'=CH3, Y = (CH2)2 (L1H2); R = CH3, R' = C6H5, Y = (CH2)2 (L2H2); R = R' = CH3, Y = (CH2)3 (L3H2); R = CH3, R' = C6H5, Y = (CH2)3 (L4H2), in 1 : 2 molar ratio give mononuclear derivatives of aluminium AlLLH (1a-1d). Equimolar reactions of AlLLH with M(OPri)3 (M = Al and B) yield homo- and hetero-dinuclear derivatives AlLLM(OPri)2 (M=Al=2a-2d M=B=3a-3d). Reaction of 2a with L1H2 affords AlL1L1AlL1 (4). All these derivatives have been characterized by elemental analysis, molecular weight measurements and plausible structures have been suggested on the basis of IR, NMR [1H, 13C, 27Al and 11B] spectral data and FAB-mass studies of 2b and 3b. Schiff base L1H2 and its mononuclear derivative with aluminium (AlL1L1H) have been screened for their antibacterial activity against Escherischia coli and Bacillus subtilis.