Uranyl and transition metal chelates of tenoxicam. Crystal structures of trans,trans-[Co(II)(Hten)2(dmso)2], trans,trans-[Zn(II)(Hten)2(dmso)2] and cis,cis-[UO2(VI)(Hten)2(H2O)] · 2C2H5OH

Author： El-Gamel Nadia Gerlach Daniela

Publisher： Taylor & Francis Ltd

ISSN： 0095-8972

Source： Journal of Coordination Chemistry, Vol.61, Iss.14, 2008-01, pp. : 2246-2265

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Abstract

The synthesis and characterization of ternary Fe(III)- (1), Co(II)- (2), Ni(II)- (3), Cu(II)- (4), Zn(II)- (5) and UO2(VI)- (6) chelates with the potent anti-inflammatory drug tenoxicam (H2ten) and (dl-alanine, Hala) are reported. All complexes are octahedral except Cu(II) and Zn(II) chelates, which are tetrahedral, and U-atoms in the uranyl chelates have a pentagonal-bipyramidal coordination sphere. The ternary Co(II) and Zn(II) complexes dissociate in dmso where orange and yellow crystals of trans,trans-[Co(II)(Hten)2(dmso)2] (8) and trans,trans-[Zn(II)(Hten)2(dmso)2] (9), respectively, were obtained. Crystallization of the binary uranyl chelate (7) from ethanol afforded the ethanol solvate cis,cis-[UO2(VI)(Hten)2(H2O)] · 2C2H5OH (7a). trans,trans-[Co(II)(Hten)2(dmso)2] (8) and trans,trans-[Zn(II)(Hten)2(dmso)2] (9) crystallize in the monoclinic space group P21/n while 7a crystallizes in the triclinic space group [image omitted]. The kinetics of the thermal decompositions for 1, 3, 4, 6 and 7 were studied and the thermodynamic parameters E*, ∆H*, ∆S* and ∆G* evaluated.