Author: Tsuneda S. Kagawa H. Saito K. Sugo T.
Publisher: Academic Press
ISSN: 0021-9797
Source: Journal of Colloid and Interface Science, Vol.176, Iss.1, 1995-12, pp. : 95-100
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Abstract
A porous hollow-fiber membrane was modified with diethylamino (DEA) and ethanolamino (EA) groups by radiation-induced graft polymerization and subsequent chemical modifications. Adsorption behavior of bovine serum albumin (BSA) was investigated by permeating a BSA buffer solution through the membrane. A polymer chain grafted onto the pore surface of the membrane held BSA in multilayers, i.e., three-dimensionally in a tentacle-like manner. The membrane with a DEA group density of 2.5 mol/kg had a binding capacity for BSA of 443 g/kg, equivalent to 11 times the monolayer adsorption. Permeation of a buffer solution containing 0.5
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