Characterization of the Electrostatic Perturbation of a Catalytic Site (Cys)-S /(His)-Im H Ion-pair in One Type of Serine Proteinase Architecture by Kinetic and Computational Studies on Chemically Mutated Subtilisin Variants

Author： Plou F.J.   Kowlessur D.   Malthouse P.J.G.   Mellor G.W.   Hartshorn M.J.   Pinitglang S.   Patel H.   Topham C.M.   Thomas E.W.   Verma C.   Brocklehurst K.  

Publisher： Academic Press

ISSN： 0022-2836

Source： Journal of Molecular Biology, Vol.257, Iss.5, 1996-04, pp. : 1088-1111

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