Dinucleosomes Show Compaction by Ionic Strength, Consistent with Bending of Linker DNA

Author: Butler P.J.G.   Thomas J.O.  

Publisher: Academic Press

ISSN: 0022-2836

Source: Journal of Molecular Biology, Vol.281, Iss.3, 1998-08, pp. : 401-407

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Abstract

Nucleosome dimers from chicken erythrocytes show an ionic strength dependence of sedimentation coefficient similar to that of trimers, and indicative of a degree of compaction over a range of low ionic strengths. This is not easily reconciled with straight linkers but is consistent with bending or kinking of the linker DNA.