Potentiating AZT Activation: Structures of Wild-type and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants’ Improved Kinetics with the HIV Prodrug Metabolite AZTMP

Author： Ostermann N.   Lavie A.   Padiyar S.   Brundiers R.   Veit T.   Reinstein J.   Goody R.S.   Konrad M.   Schlichting I.  

Publisher： Academic Press

ISSN： 0022-2836

Source： Journal of Molecular Biology, Vol.304, Iss.1, 2000-11, pp. : 43-53

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