Novel Azacyclic Ureas That Are Potent Inhibitors of HIV-1 Protease

By Sham H.L.   Zhao C.   Marsh K.C.   Betebenner D.A.   Lin S.   Jr W.R.   Herrin T.   Li L.   Madigan D.   Vasavanonda S.   Molla A.   Saldivar A.   McDonald E.   Wideburg N.E.   Kempf D.   Norbeck D.W.   Plattner J.J.  

Biochemical and Biophysical Research Communications, Vol. 225, Iss. 2, 1996-08 ,pp. : 436-440

Elsevier

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Computational Design of New Cyclic Urea Inhibitors for Improved Binding of HIV-1 Aspartic Protease

By Kotamarthi B.   Bonin I.   Benedetti F.   Miertus S.  

Biochemical and Biophysical Research Communications, Vol. 268, Iss. 2, 2000-02 ,pp. : 384-389

Elsevier

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The Binding Energetics of First- and Second-Generation HIV-1 Protease Inhibitors: Implications for Drug Design

By Velazquez-Campoy A.   Kiso Y.   Freire E.  

Archives of Biochemistry and Biophysics, Vol. 390, Iss. 2, 2001-06 ,pp. : 169-175

Elsevier

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Unusual Binding Mode of an HIV-1 Protease Inhibitor Explains its Potency against Multi-drug-resistant Virus Strains

By Weber J.   Mesters J.R.   Lepsˇı´k M.   Prejdova´ J.   Sˇvec M.   Sˇponarova´ J.   Mlcˇochova´ P.   Skalicka´ K.   Strˇı´sˇovsky´ K.   Uhlı´kova´ T.   Soucˇek M.   Machala L.   Stanˇkova´ M.   Vondra´sˇek J.   Klimkait T.   Kraeusslich H-G.   Hilgenfeld R.   Konvalinka J.  

Journal of Molecular Biology, Vol. 324, Iss. 4, 2002-12 ,pp. : 739-754

Academic Press

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The Structural Stability of the HIV-1 Protease

By Todd M.J.   Semo N.   Freire E.  

Journal of Molecular Biology, Vol. 283, Iss. 2, 1998-10 ,pp. : 475-488

Academic Press

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