Modeling Activation and Desensitization of G-Protein Coupled Receptors Provides Insight into Ligand Efficacy

Author： Riccobene T.A. Omann G.M. Linderman J.J.

ISSN： 0022-5193

Source： Journal of Theoretical Biology, Vol.200, Iss.2, 1999-09, pp. : 207-222

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

A conformation‐equilibrium model captures ligand–ligand interactions and ligand‐biased signalling by G‐protein coupled receptors

FEBS JOURNAL (ELECTRONIC), Vol. 281, Iss. 20, 2014-10 ,pp. : 4659-4671

John Wiley & Sons Inc

Access to resources Recommend Favorite

Integrating Pharmacophore into Membrane Molecular Dynamics Simulations to Improve Homology Modeling of G Protein‐coupled Receptors with Ligand Selectivity: A2A Adenosine Receptor as an Example

CHEMICAL BIOLOGY & DRUG DESIGN (ELECTRONIC), Vol. 86, Iss. 6, 2015-12 ,pp. : 1438-1450

John Wiley & Sons Inc

Access to resources Recommend Favorite

A model of non-exclusive binding of agonist and antagonist on g-protein coupled receptors

By Jarv J.

Journal of Theoretical Biology, Vol. 175, Iss. 4, 1995-04 ,pp. : 577-582

Academic Press

Access to resources Recommend Favorite

Uncovering Biases in High Throughput Screens of G-Protein Coupled Receptors

By Woolf P.J. Kenakin T.P. Linderman J.J.

Journal of Theoretical Biology, Vol. 208, Iss. 4, 2001-02 ,pp. : 403-418

Academic Press

Access to resources Recommend Favorite

On the Role of G-Protein Coupled Receptors in Cell Volume Regulation

Cellular Physiology and Biochemistry, Vol. 21, Iss. 1-3, 2008-01 ,pp. : 001-014

Karger

Access to resources Recommend Favorite