Arylsulfone-based HIV-1 non-nucleoside reverse transcriptase inhibitors

By Famiglini Valeria   Coluccia Antonio   Brancale Andrea   Pelliccia Sveva   La Regina Giuseppe   Silvestri Romano  

Future Medicinal Chemistry, Vol. 5, Iss. 18, 2013-12 ,pp. : 2141-2156

Future Science

Access to resources Recommend Favorite

Molecular basis for the enantioselectivity of HIV‐1 reverse transcriptase: role of the 3′‐hydroxyl group of the L‐()‐ribose in chiral discrimination between D‐ and L‐enantiomers of deoxy‐ and dideoxy‐nucleoside triphosphate analogs

By Maga Giovanni   Amacker Mario  

Nucleic Acids Research, Vol. 27, Iss. 4, 1999-02 ,pp. : 972-978

Oxford University Press

Access to resources Recommend Favorite

Structures of Tyr188Leu Mutant and Wild-type HIV-1 Reverse Transcriptase Complexed with the Non-nucleoside Inhibitor HBY 097: Inhibitor Flexibility is a Useful Design Feature for Reducing Drug Resistance

By Hsiou Y.   Das K.   Ding J.   Clark Jr A.D.   Kleim J-P.   Rösner M.   Winkler I.   Riess G.   Hughes S.H.   Arnold E.  

Journal of Molecular Biology, Vol. 284, Iss. 2, 1998-11 ,pp. : 313-323

Academic Press

Access to resources Recommend Favorite

Investigation of Novel Lipid-Functionalized PNA Monomers as Potential HIV-1 Non-Nucleoside Reverse Transcriptase and/or Integrase Inhibitors

By Thomas Michael   Maga Giovanni   Mouscadet Jean-François   Howarth Nicola  

Nucleosides, Nucleotides & Nucleic Acids, Vol. 26, Iss. 8-9, 2007-08 ,pp. : 1063-1066

Taylor & Francis Ltd

Access to resources Recommend Favorite

Multidrug-resistant HIV-1 Reverse Transcriptase: Involvement of Ribonucleotide-dependent Phosphorolysis in Cross-resistance to Nucleoside Analogue Inhibitors

By Mas A.   Va´zquez-A´lvarez B.M.   Domingo E.   Mene´ndez-Arias L.  

Journal of Molecular Biology, Vol. 323, Iss. 2, 2002-10 ,pp. : 181-197

Academic Press

Access to resources Recommend Favorite