Systemic sclerosis sine scleroderma associated with Wolff-Parkinson-White syndrome

Author: Park Y. -W.   Woo H.   Yoon H. -J.   Park H. -W.   Cho J. -G.   Shin S. -S.   Lee S. -S.  

Publisher: Informa Healthcare

ISSN: 0300-9742

Source: Scandinavian Journal of Rheumatology, Vol.36, Iss.1, 2007-01, pp. : 68-70

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Abstract

The term 'systemic sclerosis sine scleroderma (ssSSc)' has been used to designate a rare progressive systemic sclerosis of visceral organs without skin manifestations. A variety of visceral organs, including the gastrointestinal tract, lung, heart, and kidney, can be involved. We describe a case of 59-year-old female patient with both Wolff-Parkinson-White (WPW) syndrome and ssSSc. She was diagnosed as having ssSSc with Raynaud's phenomenon, anti-nuclear antibody (ANA) and anti-topoisomerase antibody positivity, interstitial pulmonary infiltrates, suspected pulmonary hypertension, subclinical oesophageal dysmotility but no skin thickening. She had a history of paroxysmal tachycardia together with Raynaud's phenomenon and exercise-induced dyspnoea. Electrophysiological study confirmed WPW syndrome with left posterior bypass tract. This case highlights cardiac arrhythmia caused by WPW syndrome as a clinical manifestation of the heart in ssSSc.

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