Author： Otani Atsushi Friedlander Martin
Publisher： Informa Healthcare
ISSN： 0882-0538
Source： Seminars in Ophthalmology, Vol.20, Iss.1, 2005-03, pp. : 43-50
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Abstract
We discuss the potential use of stem cells for therapeutic angiogenesis in the treatment of retinal diseases. We demonstrate that the clinical utility of these EPC may be not limited in the treatment of ischemic retinal diseases but may also have application for the treatment of retinal degenerative disorders and for a form of cell-based gene therapy. One of the greatest potential benefits of bone marrow derived EPC therapy is the possible use of autologous grafts. Nonetheless, potential toxicities and unregulated cell growth will need to be carefully evaluated before this approach is brought to the clinics.
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