Clinical Outcomes of Primary Angioplasty in ST Elevation Myocardial Infarction Patients With Antecedent Hypertension During Hospital Stay and Follow-up

Author： Ayhan Erkan Uyarel Huseyin Cicek Gokhan Ergelen Mehmet Işık Turgay Eren Mehmet

Publisher： Informa Healthcare

ISSN： 1064-1963

Source： Clinical and Experimental Hypertension, Vol.34, Iss.5, 2012-08, pp. : 357-362

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Abstract

Hypertension is a known risk factor for coronary artery disease. However, the number of studies focusing on the events following ST elevation myocardial infarction (STEMI) in patients with an antecedent hypertension is limited. Our aim is to evaluate the clinical outcomes of primary angioplasty in STEMI patients with antecedent hypertension during hospital stay and follow-up. A total of 373 patients (177 of whom had antecedent hypertension) who were treated by primary angioplasty because of STEMI were included in this study. All parameters were compared between the groups with and without hypertension. Hypertensive patients who received primary angioplasty were older (59.9 ± 12.6 vs. 52 ± 12.3, P < .001) and had higher rates of in-hospital mortality and major adverse cardiac events than patients without hypertension. Among STEMI patients, only history of hypertension for more than 10 years was a predictor of in-hospital mortality (odds ratio: 4.374, 95% CI 1.017–18.822, P = .04). Patients with an antecedent hypertension have higher initial risk profiles and show more negative outcomes during a 6-month follow-up period.