Author： JareÑo Enrique J. Romá JoaquÍn Romero Belén MarÍn Nuria Muriach MarÍa Johnsen Siv Bosch-Morell Francisco Marselou Lena Romero Francisco J.
Publisher： Informa Healthcare
ISSN： 1071-5762
Source： Free Radical Research, Vol.36, Iss.3, 2002-01, pp. : 341-344
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
Serum malondialdehyde (MDA) levels are increased in human immunodeficiency virus (HIV)-infected children, as it happens also in infected adult individuals. Introduction of high activity antiretroviral therapy (HAART) has promoted an intense decline in morbidity and mortality of these patients. Here we present data on the effect of HAART on serum MDA of HIV+ children and compare them with levels prior to HAART. MDA levels reflect, as other markers do, the HAART-induced clinical improvement and probably also the pro-oxidant/antioxidant side effects of the different drugs used. The results herein allow the proposal of including serum MDA levels as an additional parameter for the clinical management of HIV+ children.
Related content
Access to resources
Recommend
