Quality by design: optimization of a freeze-drying cycle via design space in case of heterogeneous drying behavior and influence of the freezing protocol

Author: Pisano Roberto   Fissore Davide   Barresi Antonello A.   Brayard Philippe   Chouvenc Pierre   Woinet Bertrand  

Publisher: Informa Healthcare

ISSN: 1083-7450

Source: Pharmaceutical Development and Technology, Vol.18, Iss.1, 2013-02, pp. : 280-295

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