Two novel structural classes of p38 kinase inhibitors

Author:  

Publisher: Informa Healthcare

ISSN: 1354-3776

Source: Expert Opinion on Therapeutic Patents, Vol.9, Iss.4, 1999-04, pp. : 477-480

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Abstract

Two patents claiming the use of structurally distinct p38 (mitogen-activated protein, MAP) kinase inhibitors are compared. One claims bisarylpyrazole derivatives and provides effective anti-inflammatory agents. The second claims the use of bisarylureas, which provide a novel non-azole template, as p38 inhibitors.