Author： Koch Cameron J. Kruuv Jack Frey Harold E. Snyder Robert A.
Publisher： Informa Healthcare
ISSN： 1362-3095
Source： International Journal of Radiation Biology, Vol.23, Iss.1, 1973-01, pp. : 67-74
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Abstract
Mammalian fibroblasts were incubated for four days at 37°C under hypoxic conditions. After one day the cells reached a plateau-phase in growth. After replating under aerobic conditions, various properties of the cells were investigated. It was found that they had accumulated in a pre-DNA-synthetic state. However, growth curves, DNA-synthesis data, and radiation-survival curves indicated that these cells behaved like an asynchronous population.
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