

Author: Searle A.G. Beechey C.V. Green D. Howells G.R.
Publisher: Informa Healthcare
ISSN: 1362-3095
Source: International Journal of Radiation Biology, Vol.37, Iss.2, 1980-02, pp. : 189-200
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Abstract
Breeding performances are compared of hybrid female mice given 239Pu (5 or 10 μCikg−1 body mass in 1 per cent trisodium citrate via the tail-vein), or kept in a 10 rad/day or 20 rad/day 60Co γ-irradiation field (but mated in the control area), or unirradiated. Ovarian dose-rates from the injected plutonium were initially 0·8 and 1·7 rad/day, changing little thereafter; actual γ-ray dose-rates to breeding females averaged around 8 and 16 rad/day respectively. Both γ-ray treatments affected reproductive performance more than the plutonium injections, with respect to duration of fertility and to offspring per litter in successive 4-weekly periods, though overall mean litter-sizes were not significantly less than controls. The r.b.e. for these effects on reproduction, attributed to germ-cell killing, is about 2·5 for the α-particles
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