Tumour-growth and Cell-viability of Irradiated Ehrlich Ascites Carcinoma in the Mouse

Author: Silini G.   Hornsey S.   Ebert M.  

Publisher: Informa Healthcare

ISSN: 1362-3095

Source: International Journal of Radiation Biology, Vol.5, Iss.1, 1962-04, pp. : 45-57

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Abstract

(1) Growth curves were obtained for a tetraploid strain of the Ehrlich ascites tumour of the mouse, both untreated and after irradiation.(2) Higher total cell-counts were obtained when viable and heavily-irradiated cells were mixed. This can be explained by the multiplication of the heavily-irradiated cells (which was demonstrated), rather than by stimulation of the growth of the viable fraction.(3) The method as a means of assessing cell viability after irradiation is compared with a cell-titration technique.