Prediction of metabolic drug clearance in humans: In vitro–in vivo extrapolation vs allometric scaling

By Shiran M. R.   Proctor N. J.   Howgate E. M.   Rowland-Yeo K.   Tucker G. T.   Rostami-Hodjegan A.  

Xenobiotica, Vol. 36, Iss. 7, 2006-07 ,pp. : 567-580

Informa Healthcare

Access to resources Recommend Favorite

Prediction of clinical pharmacokinetic parameters of linezolid using animal data by allometric scaling: applicability for the development of novel oxazolidinones

By Bhamidipati R. K.   Dravid P. V.   Mullangi R.   Srinivas N. R.  

Xenobiotica, Vol. 34, Iss. 6, 2004-06 ,pp. : 571-579

Informa Healthcare

Access to resources Recommend Favorite

Determination of microsome and hepatocyte scaling factors for in vitro/in vivo extrapolation in the rat and dog

By Smith R.   Jones R. D. O.   Ballard P. G.   Griffiths H. H.  

Xenobiotica, Vol. 38, Iss. 11, 2008-11 ,pp. : 1386-1398

Informa Healthcare

Access to resources Recommend Favorite

Interspecies scaling and prediction of human clearance: comparison of small- and macro-molecule drugs

By Huh Yeamin   Smith David E   Rose Feng Meihau  

Xenobiotica, Vol. 41, Iss. 11, 2011-11 ,pp. : 972-987

Informa Healthcare

Access to resources Recommend Favorite

Modelling and simulation in prediction of human xenobiotic absorption, distribution, metabolism and excretion (ADME): in vitro–in vivo extrapolations (IVIVE)

By  

Xenobiotica, Vol. 37, Iss. 10-11, 2007-11 ,pp. : 1013-1014

Informa Healthcare

Access to resources Recommend Favorite