Formation in vitro of an inhibitory cytochrome P450 Fe 2-metabolite complex with roxithromycin and its decladinosyl, O -dealkyl and N -demethyl metabolites in rat liver microsomes

Author： Yamazaki H.   Shimada T.  

Publisher： Informa Healthcare

ISSN： 1366-5928

Source： Xenobiotica, Vol.28, Iss.10, 1998-10, pp. : 995-1004

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes

By Murai K.   Yamazaki H.   Nakagawa K.   Kawai R.   Kamataki T.  

Xenobiotica, Vol. 39, Iss. 11, 2009-11 ,pp. : 795-802

Informa Healthcare

Access to resources Recommend Favorite

Characterization of triptolide hydroxylation by cytochrome P450 in human and rat liver microsomes

By Li W.   Liu Y.   He Y. -Q.   Zhang J. -W.   Gao Y.   Ge G. -B.   Liu H. -X.   Huo H.   Liu H. -T.   Wang L. -M.   Sun J.   Wang Q.   Yang L.  

Xenobiotica, Vol. 38, Iss. 12, 2008-12 ,pp. : 1551-1565

Informa Healthcare

Access to resources Recommend Favorite

In vitro metabolism of a novel PPARγ agonist, KR-62980, and its stereoisomer, KR-63198, in human liver microsomes and by recombinant cytochrome P450s

By Kim K. -B.   Seo K. -A.   Yoon Y. -J.   Bae M. -A.   Cheon H. G.   Shin J. -G.   Liu K. -H.  

Xenobiotica, Vol. 38, Iss. 9, 2008-09 ,pp. : 1165-1176

Informa Healthcare

Access to resources Recommend Favorite

In vitro metabolism of magnolin and characterization of cytochrome P450 enzymes responsible for its metabolism in human liver microsomes

By Kim Dong Kyun   Liu Kwang-Hyeon   Jeong Ji Hyun   Ji Hye Young   Oh Sei-Ryang   Lee Hyeong-Kyu   Lee Hye Suk  

Xenobiotica, Vol. 41, Iss. 5, 2011-05 ,pp. : 358-371

Informa Healthcare

Access to resources Recommend Favorite

Roles of cytochrome P450 3A enzymes in the 2-hydroxylation of 1,4-cineole, a monoterpene cyclic ether, by rat and human liver microsomes

By Miyazawa M.   Shindo M.   Shimada T.  

Xenobiotica, Vol. 31, Iss. 10, 2001-10 ,pp. : 713-723

Informa Healthcare

Access to resources Recommend Favorite