Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4

By Lewis D. F. V.   Lake B. G.   P. M. Dickins   Eddershaw J.   Tarbit M. H.   Goldfarb P. S.  

Xenobiotica, Vol. 29, Iss. 4, 1999-04 ,pp. : 361-393

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Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform

By Lewis D. F. V.   Bird M. G.   Dickins M.   Lake B. G.   Eddershaw P. J.   Tarbit M. H.   Goldfarb P. S.  

Xenobiotica, Vol. 30, Iss. 1, 2000-01 ,pp. : 1-25

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Molecular modelling of cytochrome P4502D6 (CYP2D6) based on an alignment with CYP102 : structural studies on specific CYP2D6substrate metabolism

By Lewis D. F. V.   Eddershaw P. J.   Goldfarb P. S.   Tarbit M. H.  

Xenobiotica, Vol. 27, Iss. 4, 1997-04 ,pp. : 319-340

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Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily

By Lewis D. F. V.   Dickins M.   Weaver R. J.   Eddershaw P. J.   Goldfarb P. S.   Tarbit M. H.  

Xenobiotica, Vol. 28, Iss. 3, 1998-03 ,pp. : 235-268

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Homology modelling of CYP3A4 from the CYP2C5 crystallographic template: analysis of typical CYP3A4 substrate interactions

By Lewis D. F. V.   Lake B. G.   Dickins M.   Goldfarb P. S.  

Xenobiotica, Vol. 34, Iss. 6, 2004-06 ,pp. : 549-569

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