Hepatotoxicity of ketoconazole in Sprague-Dawley rats: glutathione depletion, flavin-containing monooxygenases-mediated bioactivation and hepatic covalent binding

Author: Rodriguez R. J.   Buckholz C. J.  

Publisher: Informa Healthcare

ISSN: 1366-5928

Source: Xenobiotica, Vol.33, Iss.4, 2003-04, pp. : 429-441

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Abstract