Preclinical disposition and pharmacokinetics-pharmacodynamic modeling of biomarker response and tumour growth inhibition in xenograft mouse models of G-573, a MEK inhibitor

Author: Choo Edna F.   Belvin Marcia   Chan Jocelyn   Hoeflich Klaus   Orr Christine   Robarge Kirk   Yang Xiaoye   Zak Mark   Boggs Jason  

Publisher: Informa Healthcare

ISSN: 1366-5928

Source: Xenobiotica, Vol.40, Iss.11, 2010-11, pp. : 751-762

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