Preclinical assessment of novel BRAF inhibitors: integrating pharmacokinetic-pharmacodynamic modelling in the drug discovery process

Author： Choo Edna F   Alicke Bruno   Boggs Jason   Dinkel Vikki   Gould Stephen   Grina Jonas   West Kristina   Menghrajani Kapil   Ran Yingqing   Rudolph Joachim   Wenglowsky Steve  

Publisher： Informa Healthcare

ISSN： 1366-5928

Source： Xenobiotica, Vol.41, Iss.12, 2011-12, pp. : 1076-1087

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