Scintigraphic demonstration of myocardial perfusion and ischaemia associated with coronary artery bypass grafting

Author： Larstorp Anne Cecilie K. Lund SÃ¸raas Camilla TÃ¸nnessen Theis MÃ¼ller Carl Kjeldsen Sverre E. Mangschau Arild

ISSN： 1401-7431

Source： Scandinavian Cardiovascular Journal, Vol.40, Iss.6, 2006-12, pp. : 354-362

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Abstract

Objectives. To assess if myocardial perfusion scintigraphy (MPS) at rest can be of value in elucidating myocardial perfusion, ischaemia and perioperative myocardial infarction (PMI) associated with coronary artery bypass graft (CABG) surgery. Design. This was a prospective randomized study of patients undergoing elective CABG. Forty-eight patients in the control group underwent serial ECG recordings and measurements of CK-MB and cTnT. Fifty-four patients in the study group were additionally examined with MPS preoperatively and 2â–“4 days and 6 weeks postoperatively. Results. The study showed a highly significant (pâ–Š<â–Š0.001) improvement in myocardial radionuclide uptake from preoperatively to 2â–“4 days postoperatively. Judged from ECG and enzymatic changes, two control patients and one study patient only had PMI and no additional cases of PMI were demonstrated by MPS. Conclusion. MPS at rest showed that CABG significantly improved myocardial perfusion, by demonstrating an increase in radionuclide uptake. In diagnosing PMI, we found that MPS provided no additional information beyond cardiac biochemical markers and ECG changes.