Parathyroid hormone (1-34): a major advance in the treatment of osteoporosis?

Author: Doggrell Sheila A  

Publisher: Informa Healthcare

ISSN: 1465-6566

Source: Expert Opinion on Pharmacotherapy, Vol.2, Iss.11, 2001-11, pp. : 1919-1920

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Abstract

Osteoporosis is a major public health problem for older women and men. Parathyroid hormone (PTH) (1-34), which produces similar biological activity to the parent hormone, was tested in postmenopausal women with prior vertebral fractures. In 18 months, PTH (1-34) caused a dramatic 65% decrease in the risk of new vertebral fractures with a 10% increase in bone mineral density with few side effects. PTH (1-34) represents an exciting new therapy for this high risk group.