Ocular penetration of moxifloxacin 0.5% and gatifloxacin 0.3% ophthalmic solutions into the aqueous humor following topical administration prior to routine cataract surgery

Author： Kim Dianne H.   Stark Walter J.   O'Brien Terrence P.  

Publisher： Informa Healthcare

ISSN： 1473-4877

Source： Current Medical Research and Opinion, Vol.21, Iss.1, 2005-01, pp. : 93-94

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

A prospective, double-masked, randomized, parallel-group study (n = 25) was conducted to examine the ocular penetration of moxifloxacin 0.5% ophthalmic solution and gatifloxacin 0.3% solution into the aqueous humor following topical administration prior to routine cataract surgery. One drop of antibiotic was instilled every 10 min for four doses beginning 1 h prior to surgery. Preliminary results showed aqueous humor concentrations for moxifloxacin that were significantly greater (p < 0.01) than those for gatifloxacin.

Related content

The ocular penetration of levofloxacin 1.5% and gatifloxacin 0.3% ophthalmic solutions in subjects undergoing corneal transplant surgery

By Holland Edward J.   McCarthy Martin   Holland Simon  

Current Medical Research and Opinion, Vol. 23, Iss. 12, 2007-12 ,pp. : 2955-2960 (6)

Informa Healthcare

Access to resources Recommend Favorite

Loteprednol Etabonate Ophthalmic Gel 0.5% Following Cataract Surgery: Integrated Analysis of Two Clinical Studies

By Rajpal Rajesh   Fong Raymond   Comstock Timothy  

Advances in Therapy, Vol. 30, Iss. 10, 2013-10 ,pp. : 907-923 (17)

Springer Publishing Company

Access to resources Recommend Favorite

Ocular tolerance in rabbits of intracameral administration of MYDRANE, a fixed combination of tropicamide, phenylephrine, and lidocaine for cataract surgery

By  

ACTA OPHTHALMOLOGICA, Vol. 94, Iss. S256, 2016-10 ,pp. : n/a-n/a (NaN)

John Wiley & Sons Inc

Access to resources Recommend Favorite

Maxitrol‐induced corneal melts after routine cataract surgery in rheumatology patients

By  

CLINICAL & EXPERIMENTAL OPHTHALMOLOGY, Vol. 43, Iss. 2, 2015-03 ,pp. : 188-189 (2)

John Wiley & Sons Inc

Access to resources Recommend Favorite

Pre cataract surgery macular ocular coherence tomography: detecting ocular co morbidities and managing patient expectations

By  

CLINICAL & EXPERIMENTAL OPHTHALMOLOGY, Vol. 46, Iss. 1, 2018-01 ,pp. : 101-102 (2)

John Wiley & Sons Inc

Access to resources Recommend Favorite