Multi-targeted Antifolates Aimed at Avoiding Drug Resistance Form Covalent Closed Inhibitory Complexes with Human and Escherichia coli Thymidylate Synthases

By Sayre P.H.   Finer-Moore J.S.   Fritz T.A.   Biermann D.   Gates S.B.   MacKellar W.C.   Patel V.F.   Stroud R.M.  

Journal of Molecular Biology, Vol. 313, Iss. 4, 2001-11 ,pp. : 813-829

Academic Press

Access to resources Recommend Favorite

The Role of Mg²⁺and Specific Amino Acid Residues in the Catalytic Reaction of the Major Human Abasic Endonuclease: New Insights from EDTA-resistant Incision of Acyclic Abasic Site Analogs and Site-directed Mutagenesis

By Erzberger J.P.   Wilson III D.M.  

Journal of Molecular Biology, Vol. 290, Iss. 2, 1999-07 ,pp. : 447-457

Academic Press

Access to resources Recommend Favorite

Role of cysteine amino acid residues on the RNA binding activity of human thymidylate synthase

By Lin Xiukun   Liu Jun   Maley Frank  

Nucleic Acids Research, Vol. 31, Iss. 16, 2003-08 ,pp. : 4882-4887

Oxford University Press

Access to resources Recommend Favorite

Identification of the Acidic Residues in the Active Site of DNA Polymerase III

By Pritchard A.E.   McHenry C.S.  

Journal of Molecular Biology, Vol. 285, Iss. 3, 1999-01 ,pp. : 1067-1080

Academic Press

Access to resources Recommend Favorite

The roles of active site residues in the catalytic mechanism of methylaspartate ammonia‐lyase

By  

FEBS Open Bio, Vol. 3, Iss. 1, 2013-01 ,pp. : 285-290

John Wiley & Sons Inc

Access to resources Recommend Favorite