Single-strand nicks induce homologous recombination with less toxicity than double-strand breaks using an AAV vector template

Author： Metzger Michael J.  

Publisher： Oxford University Press

ISSN： 1362-4962

Source： Nucleic Acids Research, Vol.39, Iss.3, 2011-02, pp. : 926-935

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Homologous recombination and the roles of double-strand breaks

By Shinohara A.   Ogawa T.  

Trends in Biochemical Sciences, Vol. 20, Iss. 10, 1995-10 ,pp. : 387-391

Elsevier

Access to resources Recommend Favorite

An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells

By Han M.  

Nucleic Acids Research, Vol. 30, Iss. 15, 2002-08 ,pp. : 3454-3463

Oxford University Press

Access to resources Recommend Favorite

GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination

By Takizawa Yoshimasa  

Nucleic Acids Research, Vol. 38, Iss. 15, 2010-08 ,pp. : 5059-5074

Oxford University Press

Access to resources Recommend Favorite

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

By Bolderson Emma  

Nucleic Acids Research, Vol. 38, Iss. 6, 2010-04 ,pp. : 1821-1831

Oxford University Press

Access to resources Recommend Favorite

Conservative homologous recombination preferentially repairs DNA double-strand breaks in the S phase of the cell cycle in human cells

By Saleh-Gohari Nasrollah   Helleday Thomas  

Nucleic Acids Research, Vol. 32, Iss. 12, 2004-01 ,pp. : 3683-3688

Oxford University Press

Access to resources Recommend Favorite