A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly

Author: Chen Shijia   Oikonomou Grigorios   Chiu Cindy N.   Niles Brett J.   Liu Justin   Lee Daniel A.   Antoshechkin Igor   Prober David A.  

Publisher: Oxford University Press

ISSN: 1362-4962

Source: Nucleic Acids Research, Vol.41, Iss.4, 2013-02, pp. : 2769-2778

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Abstract