

Author: Schulte T.
Publisher: Oxford University Press
ISSN: 1460-2199
Source: Cerebral Cortex, Vol.15, Iss.9, 2005-09, pp. : 1384-1392
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Abstract
Normal aging and chronic alcoholism result in disruption of brain white matter microstructure that does not typically cause complete lesions but may underlie degradation of functions requiring interhemispheric information transfer. We examined whether the microstructural integrity of the corpus callosum assessed with diffusion tensor imaging (DTI) would relate to interhemispheric processing speed. DTI yields estimates of fractional anisotropy (FA), a measure of orientation and intravoxel coherence of water diffusion usually in white matter fibers, and diffusivity (
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