Structural Determinants of Progesterone Hydroxylation by Cytochrome P450 2B5: The Role of Nonsubstrate Recognition Site Residues

By He Y.Q.   Harlow G.R.   Szklarz G.D.   Halpert J.R.  

Archives of Biochemistry and Biophysics, Vol. 350, Iss. 2, 1998-02 ,pp. : 333-339

Elsevier

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Analysis of Four Residues within Substrate Recognition Site 4 of Human Cytochrome P450 3A4: Role in Steroid Hydroxylase Activity and alpha-Naphthoflavone Stimulation

By Domanski T.L.   Liu J.   Harlow G.R.   Halpert J.R.  

Archives of Biochemistry and Biophysics, Vol. 350, Iss. 2, 1998-02 ,pp. : 223-232

Elsevier

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Structure–Function Analysis of Human Cytochrome P450 3A4 Using 7-Alkoxycoumarins as Active-Site Probes

By Khan K.K.   Halpert J.R.  

Archives of Biochemistry and Biophysics, Vol. 373, Iss. 2, 2000-01 ,pp. : 335-345

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Interconversion of the Androstenedione Hydroxylase Specificities of Cytochromes P450 2B4 and 2B5 upon Simultaneous Site-Directed Mutagenesis of Four Key Substrate Recognition Residues

By He Y.Q.   Szklarz G.D.   Halpert J.R.  

Archives of Biochemistry and Biophysics, Vol. 335, Iss. 1, 1996-11 ,pp. : 152-160

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Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4

By Lewis D. F. V.   Lake B. G.   P. M. Dickins   Eddershaw J.   Tarbit M. H.   Goldfarb P. S.  

Xenobiotica, Vol. 29, Iss. 4, 1999-04 ,pp. : 361-393

Informa Healthcare

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