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Author: Nakai M. Tabira Y. Asai D. Yakabe Y. Shimyozu T. Noguchi M. Takatsuki M. Shimohigashi Y.
Publisher: Elsevier
ISSN: 0006-291X
Source: Biochemical and Biophysical Research Communications, Vol.254, Iss.2, 1999-01, pp. : 311-314
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Abstract
Dialkyl phthalates have been suggested to function as xenoestrogen. To explore the structural essentials, a series of ring and alkyl-chain isomers of dialkyl phthalates C6H4(COOCnHm)2 were examined for their ability to displace [3H]17β-estradiol in the recombinant human estrogen receptor expressed on Sf9 vaculovirus. Compounds with an alkyl chain of more than C3 (
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