Mungin, a Novel Cyclophilin-like Antifungal Protein from the Mung Bean

Author： Ye X.Y.   Ng T.B.  

Publisher： Elsevier

ISSN： 0006-291X

Source： Biochemical and Biophysical Research Communications, Vol.273, Iss.3, 2000-07, pp. : 1111-1115

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Abstract

A protein designated mungin, isolated from mung bean (Phaseolus mungo) seeds, possessed activity against the fungi Rhizoctonia solani, Coprinus comatus, Mycosphaerella arachidicola, Botrytis cinerea, and Fusarium oxysporum. The 18-kDa protein also possessed a novel N-terminal sequence with similarity to cyclophilins. It exerts an inhibitory action against α- and β-glucosidases suppresses [3H]thymidine in corporation by mouse splenocytes.

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